Question: what plant or animal do we share the least DNA with?

Neil Keddie answered on 6 Mar 2018:

Hi Steve, all living on earth things share the same DNA between them, with only four different molecules (base pairs, A, C, G and T) making up our DNA. What makes the DNA of any organism unique is the order of the base pairs). Specific sequences of these base pairs make up a region called a gene, which is a code to make an enzyme (a protein complex) that has a specific purpose (for example an amylase helps us to break down starch in food). We share a lot of similar genes between species, but also each species has a number that are unique to it, usually as they have adapted through evolution to help that species of organism survive in its environment.

Different species can develop similar genes independently of each other (so not necessarily related by evolution) in response to pressure to evolve in similar environments, so might end up with similar (but not identical) bits of DNA. What I’m trying to say is that we may have a lot of similarities between plants and animals in parts of our DNA, but it is the unique sequences that make our genes that make us human rather than plant to animal.